The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils
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چکیده
منابع مشابه
The T Cell Response to Staphylococcus aureus
Staphylococcus aureus (S. aureus) is a dangerous pathogen and a leading cause of both nosocomial and community acquired bacterial infection worldwide. However, on the other hand, we are all exposed to this bacterium, often within the first hours of life, and usually manage to establish equilibrium and coexist with it. What does the adaptive immune system contribute toward lifelong control of S....
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Staphylococcus aureus is an important human pathogen and commensal, where the human nose is the predominant reservoir. To better understand its behavior in this environmental niche, RNA was extracted from the anterior nares of three documented S. aureus carriers and the metatranscriptome analyzed by RNAseq. In addition, the in vivo transcriptomes were compared to previously published transcript...
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Plasma fibronectin binds to gelatin and is thought to mediate the removal of blood-borne particles by the reticuloendothelial system. This removal has primarily been studied using gelatin-coated colloidal particles. Fibronectin also binds to gram-positive bacteria. We tested the possibility that fibronectin might act as an opsonin for phagocytosis of bacteria by neutrophils. When fibronectin in...
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Neutrophils have long been regarded as essential for host defense against Staphylococcus aureus infection. However, survival of the pathogen inside various cells, including phagocytes, has been proposed as a mechanism for persistence of this microorganism in certain infections. Therefore, we investigated whether survival of the pathogen inside polymorphonuclear neutrophils (PMN) contributes to ...
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Background: The nosocomial infections that cause the establishment of biofilms on the embedded biomedical surfaces are the leading cause of sepsis and are often related to colonization of implants by Staphylococcus epidermidis. Materials and Methods: A total of 40 clinical S. aureus isolates were collected from Zabol, Iran. The ability of these strains to form biofilm was determined by microli...
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ژورنال
عنوان ژورنال: Autophagy
سال: 2020
ISSN: 1554-8627,1554-8635
DOI: 10.1080/15548627.2020.1739443